[Press Release] Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress

An international research group that includes Assoc. Prof. Masanori Ochiai (Division of Biosphere Science) first identified a receptor for the growth-blocking peptide (GBP) cytokine in the fruit fly Drosophila melanogaster, a routine model for analysis of cytokine signaling pathways in higher animals. The GBP is a multifunctional cytokine that regulates immunity and metabolism in response to various environmental stresses.
They found that the receptor not only plays important roles in environmental stress responses but also influences lifespan of the fly. The present study provides fundamental knowledge on health and longevity.

This research outcome is published in the PNAS.

Please visit links below to view the press release (Japanese ver. only).
Research Press Release (PDF)